1223405-99-9

Upstream product

• 61329-67-7 methyl 4-O-acetyl-2,3-di-O-benzyl-α-D-glucopyranoside 
• 3740-52-1 2-(2-nitrophenyl)acetic acid 

Downstream Products

• 61329-67-7 methyl 4-O-acetyl-2,3-di-O-benzyl-α-D-glucopyranoside 
• 20771-21-5 methyl 2,3-di-O-benzyl-6-O-acetyl-α-D-glucopyranoside 

Relevant academic research and scientific papers

(2-Nitrophenyl)acetyl: A new, selectively removable hydroxyl protecting group

Figure presented The utility of the (2-nitrophenyl)acetyl (NPAc) group for the protection of hydroxyl functions is reported. (2-Nitrophenyl)acetates are readily prepared starting from the commercially available, inexpensive (2-nitrophenyl)acetic acid, and these esters are stable under a series of common carbohydrate transformations. The NPAc group can be removed selectively using Zn and NH4Cl without affecting a series of common protecting groups. This new protecting group is orthogonal with the commonly used tert-butyldimethylsilyl, levulinoyl, 9-fluorenylmethoxycarbonyl, naphthylmethyl, and p-methoxybenzyl groups.