1223418-36-7Relevant articles and documents
p-TsOH promoted Fischer indole synthesis of multi-substituted 2-trifluoromethyl indole derivatives
Jiang, Haizhen,Wang, Yangli,Wan, Wen,Hao, Jian
experimental part, p. 2746 - 2751 (2010/05/02)
A p-TsOH promoted one-pot synthesis of multi-substituted 2-trifluoromethyl indole derivatives, for instance, 2-trifluoromethyl-3-phenylindoles, 2-trifluoromethyl-indole-3-propanoates, and 2-trifluoromethyl-indole-3-butanoates from reactions of 1,1,1-trifluoro-3-phenylacetone and simply prepared ω-trifluoromethyl substituted δ and ε-ketoesters with arylhydrazines via Fischer indole synthesis has been developed.