1223487-79-3Relevant academic research and scientific papers
Synthesis of phenanthroindolizidine alkaloids with an acyloxy group at the C3 position and their antitumor activities and toxicities
Ikeda, Takashi,Yaegashi, Takashi,Matsuzaki, Takeshi,Yamazaki, Ryuta,Ueno, Satoshi,Hashimoto, Syusuke,Sawada, Seigo
, p. 447 - 453 (2012)
We previously reported that the phenanthroindolizidine alkaloid 3 and its derivatives had markedly potent in vitro cytotoxicity. However, they had low in vivo antitumor activities and high in vivo toxicities, which was a serious problem for further develo
