1223487-79-3Relevant articles and documents
Synthesis of phenanthroindolizidine alkaloids with an acyloxy group at the C3 position and their antitumor activities and toxicities
Ikeda, Takashi,Yaegashi, Takashi,Matsuzaki, Takeshi,Yamazaki, Ryuta,Ueno, Satoshi,Hashimoto, Syusuke,Sawada, Seigo
, p. 447 - 453 (2012)
We previously reported that the phenanthroindolizidine alkaloid 3 and its derivatives had markedly potent in vitro cytotoxicity. However, they had low in vivo antitumor activities and high in vivo toxicities, which was a serious problem for further develo