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N-ethyl-N-methyl-3-(pyrrolidin-3-yl)benzamide hydrochloride, also known as PNU-282987, is a chemical compound that functions as a selective α7 nicotinic acetylcholine receptor agonist. It is utilized in scientific research to explore the impacts of α7 nicotinic acetylcholine receptor activation on neurotransmission and behavior. The hydrochloride salt form of N-ethyl-N-methyl-3-(pyrrolidin-3-yl)benzamide hydrochloride enhances its water solubility, facilitating its application in biological experiments. It has been considered for potential therapeutic uses, particularly in addressing neurological disorders and cognitive deficits, while requiring careful handling and adherence to safety protocols.

1223748-27-3

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1223748-27-3 Usage

Uses

Used in Scientific Research:
N-ethyl-N-methyl-3-(pyrrolidin-3-yl)benzamide hydrochloride is used as a research tool for studying the role of α7 nicotinic acetylcholine receptors in neurotransmission and behavior. It aids in understanding the receptor's function and its potential involvement in various neurological processes.
Used in Pharmaceutical Development:
In the pharmaceutical industry, N-ethyl-N-methyl-3-(pyrrolidin-3-yl)benzamide hydrochloride is used as a lead compound in the development of drugs targeting neurological disorders and cognitive deficits. Its agonistic effect on the α7 nicotinic acetylcholine receptor suggests its potential in treating conditions related to cognitive impairment and neurodegenerative diseases.
Used in Neurological Disorder Treatment:
N-ethyl-N-methyl-3-(pyrrolidin-3-yl)benzamide hydrochloride is being investigated for its therapeutic potential in the treatment of neurological disorders. Its ability to modulate neurotransmission through the α7 nicotinic acetylcholine receptor may offer benefits in managing symptoms and potentially slowing disease progression in conditions such as Alzheimer's disease, schizophrenia, and other cognitive impairments.
Used in Cognitive Deficit Management:
N-ethyl-N-methyl-3-(pyrrolidin-3-yl)benzamide hydrochloride is also considered for use in managing cognitive deficits, where the enhancement of α7 nicotinic acetylcholine receptor activity may improve cognitive function and memory. Its application in this area is still under investigation, but the preliminary findings suggest its potential as a cognitive enhancer.

Check Digit Verification of cas no

The CAS Registry Mumber 1223748-27-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,3,7,4 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1223748-27:
(9*1)+(8*2)+(7*2)+(6*3)+(5*7)+(4*4)+(3*8)+(2*2)+(1*7)=143
143 % 10 = 3
So 1223748-27-3 is a valid CAS Registry Number.

1223748-27-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name N-ethyl-N-methyl-3-pyrrolidin-3-ylbenzamide,hydrochloride

1.2 Other means of identification

Product number -
Other names N-ethyl-N-methyl-3-(pyrrolidin-3-yl)benzamide hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1223748-27-3 SDS

1223748-27-3Upstream product

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