122399-90-0

Basic information

• Product Name: (E)-4-(4-(benzyloxy)phenyl)-4-oxobut-2-enoic acid
• CAS NO: 122399-90-0
• Molecular Weight: 282.296
• Mol File: 122399-90-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-4-(4-(benzyloxy)phenyl)-4-oxobut-2-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-(4-(benzyloxy)phenyl)-4-oxobut-2-enoic acid(122399-90-0)
• EPA Substance Registry System: (E)-4-(4-(benzyloxy)phenyl)-4-oxobut-2-enoic acid(122399-90-0)

Safety Data

• Hazardous Substances Data: 122399-90-0(Hazardous Substances Data)

Upstream product

• 54696-05-8 4'-benzyloxy-acetophenone 
• 298-12-4 Glyoxilic acid 
• 122399-83-1 3-(4-benzyloxybenzoyl)-2-hydroxypropionic acid 

Relevant articles and documents

Design, synthesis, and bioevaluation of a novel class of (E)-4-oxo-crotonamide derivatives as potent antituberculosis agents

A series of novel (E)-4-oxo-2-crotonamide derivatives were designed and synthesized to find potent antituberculosis agents. All the target compounds were evaluated for their in vitro activity against Mycobacterium tuberculosis H37Rv(MTB). Results reveal that 4-phenyl moiety at part A and short methyl group at part C were found to be favorable. Most of the derivatives displayed promising activity against MTB with MIC ranging from 0.125 to 4 μg/mL. Especially, compound IIIa16 was found to have the best activity with MIC of 0.125 μg/mL against MTB and with MIC in the range of 0.05–0.48 μg/mL against drug-resistant clinical MTB isolates.

Studies on hypolipidemic agents. IV. 3-[4-(phenylthio)benzoyl]propionic acid derivatives

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