1224048-09-2 Usage
General Description
2-Pyrrolidinecarboxamide, N-[[4-[(4,4-dimethylcyclohexyl)oxy]-5-fluoro-2-methoxyphenyl]methyl]-, (2S)- is a chemical compound that is composed of a pyrrolidine ring, a fluorinated phenyl group, a methoxy group, and a cyclohexyl group. It exists in a specific stereochemical configuration known as (2S)-. 2-PyrrolidinecarboxaMide, N-[[4-[(4,4-diMethylcyclohexyl)oxy]-5-fluoro-2-Methoxyphenyl]Methyl]-, (2S)- may have potential pharmaceutical applications due to its structural features, which can potentially interact with biological targets in the human body. Its specific properties and potential uses would need to be further investigated through research and testing.
Check Digit Verification of cas no
The CAS Registry Mumber 1224048-09-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,4,0,4 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1224048-09:
(9*1)+(8*2)+(7*2)+(6*4)+(5*0)+(4*4)+(3*8)+(2*0)+(1*9)=112
112 % 10 = 2
So 1224048-09-2 is a valid CAS Registry Number.
1224048-09-2Relevant articles and documents
Orally active and brain permeable proline amides as highly selective 5HT2c agonists for the treatment of obesity
Liu, Kevin K.-C.,Lefker, Bruce A.,Dombroski, Mark A.,Chiang, Phoebe,Cornelius, Peter,Patterson, Terrell A.,Zeng, Yuan,Santucci, Stephanie,Tomlinson, Elizabeth,Gibbons, Colleen P.,Marala, Ravi,Brown, Janice A.,Kong, Jimmy X.,Lee, Eunsun,Werner, Wendy,Wenzel, Zane,Giragossian, Craig,Chen, Hou,Coffey, Steven B.
scheme or table, p. 2365 - 2369 (2010/09/03)
Brain-penetrable proline amides were developed as 5HT2c agonists with more than 1000-fold binding selectivity against 5HT2b receptor. After medicinal chemistry optimization and SAR studies, orally active proline amides with robust efficacy in a rodent foo