1224098-18-3Relevant academic research and scientific papers
Asymmetric, organocatalytic, three-step synthesis of α-hydroxy-(E)- β,γ-unsaturated Esters
Hess, Lindsey C.,Posner, Gary H.
scheme or table, p. 2120 - 2122 (2010/08/05)
Figure presented An efficient and enantiocontrolled three-step synthesis of α-hydroxy-(E)-β,γ-unsaturated esters is reported. Enantioenriched α-selenyl aldehydes, prepared in one step by asymmetric, organocatalytic α-selenylation of aldehydes, were direct
α-chloro-β,γ-ethylenic esters: Enantiocontrolled synthesis and substitutions
Genna, Douglas T.,Hencken, Christopher P.,Siegler, Maxime A.,Posner, Gary H.
supporting information; experimental part, p. 4694 - 4697 (2011/01/12)
Chiral nonracemic γ-seleno-α,β-ethylenic esters, when treated with sulfuryl chloride and ethyl vinyl ether in hexanes, produced α-chloro-β,γ-ethylenic esters in 65 - 75% yields, with ee values of 95 - 97%, and with 1,3-syn transfer of chirality. Reaction
