122431-24-7

Basic information

• Product Name: O,O-Diethyl O-1-phenyl-3-trifluoro methylpyrazol-5-ylphosphorothioate
• Synonyms: O,O-Diethyl O-1-phenyl-3-trifluoro methylpyrazol-5-ylphosphorothioate;diethoxy-[2-phenyl-5-(trifluoromethyl)pyrazol-3-yl]oxy-sulfanylidene-$l^{5}-phosphane
• CAS NO: 122431-24-7
• Molecular Formula: C14H16F3N2O3PS
• Molecular Weight: 380.3224106
• Product Categories: Agro-Products, Heterocycles, Sulfur & Selenium Compounds
• Mol File: 122431-24-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 403.9°Cat760mmHg
• Flash Point: 198.1°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.54
• Water Solubility: 0.8 mg l-1 (25 °C)
• CAS DataBase Reference: O,O-Diethyl O-1-phenyl-3-trifluoro methylpyrazol-5-ylphosphorothioate(CAS DataBase Reference)
• NIST Chemistry Reference: O,O-Diethyl O-1-phenyl-3-trifluoro methylpyrazol-5-ylphosphorothioate(122431-24-7)
• EPA Substance Registry System: O,O-Diethyl O-1-phenyl-3-trifluoro methylpyrazol-5-ylphosphorothioate(122431-24-7)

Safety Data

• Hazardous Substances Data: 122431-24-7(Hazardous Substances Data)

Usage

Description

Water solubility of flupyrazofos is 0.8 mg/L. Log Kow = 5.24. Flupyrazofos is slowly hydrolyzed in aqueous media; DT50 at pH 4, 7, and 9 are 266, 180, and 121 h, respectively. Vp 3.7 mPa (25 ?C). Flupyrazofos is a nonsystemic insecticide used for the control of caterpillars, especially diamondblack moth, Plutella xylostella, larvae.

Uses

Different sources of media describe the Uses of 122431-24-7 differently. You can refer to the following data:
1. Flupyrazofos is a new pyrazole organophosporus insecticide, which has a high activity against the diamond-back moth (Plutella xylostella).
2. Flupyrazofos is a new insecticide under development which has shown good activity against caterpillars, especially Plutella xylostella larvae.

Metabolic pathway

The principal route of metabolism of flupyrazofos is by oxidative desulfuration to the oxon which is hydrolysed, principally via base rather than esterase catalysis, to 1-phenyl-3-trifluoromethyl-5-hydroxypyrazole. The physico-chemical parameters of flupyrazofos, including water solubility, hydrolysis rates, vapour pressure and octanol/water partition coefficients, have been reported by Kim et al. (1997).

Metabolism

The principal route of metabolism of flupyrazofos is by oxidative desulfuration to the oxon, followed by hydrolysis to 1- phenyl-3-trifluoromethyl-5-hydroxypyrazole and diethyl hydrogen phosphate. Flupyrazofos is degraded in soil with DT50 of about 14 d.

Toxicity evaluation

Acute oral LD50 for rats is 372–605 mg/kg.

Degradation

The hydrolytic half-life at pH values 4, 7 and 9 was 266, 180 and 121 hours, respectively (Kim et al., 1997). Flupyrazofos showed good photostability. The photodegradation products which were identified were flupyrazofos oxon (2), 1-phenyl-3-trifluoromethyl-5-hydroxypyrazole (3) and the thiono-thiolo rearranged isomer O,S-diethyl O-(1-phenyl-3- trifluoromethyl)pyrazol-5-yl phosphorothioate (4) (Cho et al., 1993) (Scheme 1).

InChI:InChI=1/C14H16F3N2O3PS/c1-3-20-23(24,21-4-2)22-12-10-19(11-8-6-5-7-9-11)18-13(12)14(15,16)17/h5-10H,3-4H2,1-2H3

Downstream Products

• 96145-98-1 1-phenyl-3-trifluoromethyl-5-hydroxypyrazole