1224439-42-2 Usage
Description
(Isobutyr-d7)-amide, a deuterated form of isobutyric acid amide, is a stable isotope labeled compound that is widely utilized in research and analytical applications. It features deuterium atoms replacing the standard hydrogen atoms, which enhances its utility for precise and accurate measurements in various scientific studies and testing procedures.
Uses
Used in Mass Spectrometry:
(Isobutyr-d7)-amide is used as an internal standard for mass spectrometry, allowing for the accurate quantification of specific compounds in biological samples. The presence of deuterium atoms in the compound provides a reliable reference point, ensuring that measurements are precise and consistent.
Used in Analytical Techniques:
In addition to mass spectrometry, (Isobutyr-d7)-amide is employed as an internal standard in other analytical techniques. Its stable isotope labeling makes it an ideal candidate for enhancing the accuracy and reliability of measurements across different scientific disciplines.
Used in Pharmaceutical Research:
(Isobutyr-d7)-amide is utilized in pharmaceutical research as a tool for studying drug metabolism and pharmacokinetics. The deuterated compound can help researchers understand how drugs are processed and eliminated from the body, ultimately contributing to the development of more effective medications.
Used in Chemical Synthesis:
(Isobutyr-d7)-amide is also used in chemical synthesis, particularly when deuterated compounds are required for specific applications. The incorporation of deuterium atoms can provide valuable insights into reaction mechanisms and help optimize synthetic processes.
Used in Material Science:
In material science, (Isobutyr-d7)-amide can be employed to study the properties of materials at the molecular level. The deuterated compound can help researchers understand how materials interact with other substances and how their properties can be manipulated for various applications.
Used in Environmental Studies:
(Isobutyr-d7)-amide is used in environmental studies to track and analyze the behavior of specific compounds in ecosystems. The deuterated compound can provide valuable information about the fate and transport of pollutants, as well as their impact on the environment and living organisms.
Used in Food Industry:
In the food industry, (Isobutyr-d7)-amide can be used to study the effects of various additives and preservatives on the quality and shelf life of food products. The deuterated compound can help researchers understand how these additives interact with food components and how they can be optimized for better food safety and preservation.
Used in Cosmetics Industry:
(Isobutyr-d7)-amide is employed in the cosmetics industry for studying the effects of various ingredients on skin health and appearance. The deuterated compound can provide insights into the mechanisms of action of cosmetic products, leading to the development of more effective and safer formulations.
Check Digit Verification of cas no
The CAS Registry Mumber 1224439-42-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,4,4,3 and 9 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1224439-42:
(9*1)+(8*2)+(7*2)+(6*4)+(5*4)+(4*3)+(3*9)+(2*4)+(1*2)=132
132 % 10 = 2
So 1224439-42-2 is a valid CAS Registry Number.
1224439-42-2Relevant articles and documents
Synthesis and pharmacokinetic profile of highly deuterated brecanavir analogs
Velthuisen, Emile J.,Baughman, Todd M.,Johns, Brian A.,Temelkoff, David P.,Weatherhead, Jason G.
, p. 202 - 212 (2013/07/27)
Several highly deuterated analogs of the HIV-1 protease inhibitor brecanavir have been prepared to study the effect of deuterium upon metabolic stability. The sites for deuterium incorporation were initially chosen to maximize the potential for a kinetic isotope effect; locations where C-H bond breaking is the rate limiting step. The analogs have been profiled in both in vitro and in vivo pharmacokinetic studies and the result will be described herein.
HYDROXYETHYLAMINO SULFONAMIDE DERIVATIVES
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Page/Page column 41, (2010/05/13)
This invention relates to novel hydroxyethylamino sulfonamides and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a compound with the ability to act as an HIV (human immunodeficiency virus) protease inhibitor.
