122453-02-5

Basic information

• Product Name: 1H-Pyrrole-3-carbonitrile, 2-(4-chlorophenyl)-
• CAS NO: 122453-02-5
• Molecular Formula: C11H7ClN2
• Molecular Weight: 202.643
• Mol File: 122453-02-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-carbonitrile, 2-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-carbonitrile, 2-(4-chlorophenyl)-(122453-02-5)
• EPA Substance Registry System: 1H-Pyrrole-3-carbonitrile, 2-(4-chlorophenyl)-(122453-02-5)

Safety Data

• Hazardous Substances Data: 122453-02-5(Hazardous Substances Data)

Usage

Structure

A pyrrole derivative with a carbonitrile group and a 4-chlorophenyl substituent

Usage

Commonly used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical drugs and active ingredients

Biological activities

Studied for its potential antifungal and anticancer properties

Versatility

Utilized in the development and production of various medicinal and pharmaceutical products.

Upstream product

• 6212-33-5 2-(4-Chlorophenyl)glycine 
• 920-37-6 2-Chloroacrylonitrile 

Downstream Products

• 122452-96-4 4,5-Dichloro-2-(p-chlorophenyl)pyrrole-3-carbonitrile 

Relevant articles and documents

Application of 2-aryl substituted pyrrole compound in medicine for killing oncomelania hupensis

The invention relates to an application of 2-aryl substituted pyrrole compound in a medicine for killing oncomelania hupensis and belongs to the technical field of prevention and treatment of bilharziasis, and particularly provides the chemical structure of the 2-aryl substituted pyrrole compound and a preparation method of same. The 2-aryl substituted pyrrole compound, being an active component,is used for preparing the snail killing agent in the forms of suspending agents, emulsions and micro-emulsions for killing the oncomelania hupensis. Immersion killing use amount of the 2-aryl substituted pyrrole compound being the active component of the snail killing agent is 0.1-10.00 mg/l, and immersion killing time is 24-72 h. The use amount of spray application is 1-10 g/m and action timeis 3-7 days. Experiment proves that the 2-aryl substituted pyrrole compound has killing activity on the oncomelania hupensis and is lower than a snail killing agent, niclosamide, in the prior art in toxicity on aquatic organisms. The compound can be processed to prepare the snail killing agents and applied in the field of prevention and treatment of bilharziasis.

Method of controlling phytopathogenic fungi

This invention is directed to a method for the control of phytopathogenic fungi by contacting the same with a cyano- or nitroarylpyrrole compound, or by applying said pyrrole compound to the foliage of a plant susceptible to disease caused by said pathogens.

α-(2,3-Di(C1 -C4 alkoxy)ethylamino)-β-cyanostyrene and β-nitrostyrene compounds useful as intermediates in the preparation of insecticidal, acaricidal and nematicidal arylpyrroles and method for the preparation thereof

This invention provides novel α-[2,2-di(C1 -C4 alkoxy)ethylamino]-β-cyanostyrene and α-[2,2-di(C1 -C4 alkoxy)ethylamino]-β-nitrostyrene compounds that are useful for the preparation of pesticidal arylpyrroles. T