122454-22-2

Basic information

• Product Name: C₁₀H₅ClF₃NO₂
• CAS NO: 122454-22-2
• Molecular Weight: 263.603
• Mol File: 122454-22-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₀H₅ClF₃NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₅ClF₃NO₂(122454-22-2)
• EPA Substance Registry System: C₁₀H₅ClF₃NO₂(122454-22-2)

Safety Data

• Hazardous Substances Data: 122454-22-2(Hazardous Substances Data)

Upstream product

• 6212-33-5 2-(4-Chlorophenyl)glycine 
• 76-05-1 trifluoroacetic acid 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 122454-23-3 2-(p-chlorophenyl)-5-(trifluoromethyl)-pyrrole-3-carbonitrile 

Relevant articles and documents

Synthesis, insecticidal and acaricidal activities of novel 2-arylpyrroles

To search for novel 2-arylpyrroles with unique biological activities, a series of novel 2-arylpyrrole derivatives were designed and synthesized, and their structures were characterized by 1H and 13C NMR spectroscopy, MS spectrometry, and elemental analysis. Their insecticidal activities against Lepidopteran pests (e.g. Mythimna separata) and acaricidal activities against mites (e.g. Tetranychus urticae) were evaluated. The results of bioassays indicate that some of these title compounds exhibited excellent insecticidal and acaricidal activities. For example, 4-bromo-1-((chloromethoxy) methyl)-2-(4-chloro phenyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile (6a), 4-bromo-2-(4-chlorophenyl)-1-((2-fluoroethoxy)-methyl)-5-(trifluoromethyl) pyrrole-3-carbonitrile (6d) showed insecticidal activity against Mythimna separata and 4-bromo-2-(4-chlorophenyl)-1-((isopropoxymethoxy)methyl)-5- (trifluoro methyl)pyrrole-3-carbonitrile (7d) showed acaricidal activity against Tetranychus urticae. They were more effective than Chlorfenapyr, which has been the only commercialized member of a new class of chemicals of 2-arylpyrroles.