122456-57-9Relevant academic research and scientific papers
Process for preparing 1-aryl-4-oxopyrrolo ?3,2-c! quinoline derivatives
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, (2008/06/13)
The present invention relates to a process for preparing 1-aryl-4-oxopyrrolo?3,2-c!quinoline derivatives through reaction of 4-oxofuro?3,2-c! quinoline compounds with aniline compounds under mild conditions in a single step, wherein 1-aryl-4-oxopyrrolo?3,
A facile method for direct conversion of dihydrofuroquinolones to dihydropyrroloquinolones
Kim, Sung Soo,Cheon, Hyac Gyeong,Kang, Seung Kyu,Yum, Eul Kgun,Choi, Joong-Kwon
, p. 221 - 226 (2007/10/03)
A novel and efficient method is described for one-step conversion of dihydrofuroquinolones to dihydropyrroloquinolones in high yields under mild conditions.
Reversible Inhibitors of the Gastric (H+/K+)-ATPase. 2. 1-Arylpyrroloquinolines: Effect of the 4-Substituent
Leach, Colin A.,Brown, Thomas H.,Ife, Robert J.,Keeling, David J.,Laing, Shiona M.,et al.
, p. 1845 - 1852 (2007/10/02)
Further work on compounds 1 has identified the 4-position as a site where substantial modifications are tolerated, leading to analogues which are more potent and less toxic than those described previously.The best compound in the series is 13a (SKandF 963
DIHYDROPYRROLO QUINOLINE DERIVATIVES
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, (2008/06/13)
1,4-Substituted 2,3-dihydropyrrolo[3,2-c]quinolines which are inhibitors of H+ K+ ATPase activity and useful as inhibitors of gastric acid secretion. A compound of the invention is 1-(2-methylphenyl)-4-amino-6-methyl-2,3-dihydropyrrolo[3,2-c]quinoline.
