1224594-42-6Relevant articles and documents
Design, asymmetric synthesis, and evaluation of pseudosymmetric sulfoximine inhibitors against HIV-1 protease
Lu, Ding,Sham, Yuk Yin,Vince, Robert
, p. 2037 - 2048 (2010)
The HIV-1 protease is a validated drug target for the design of antiretroviral drugs to combat AIDS. We previously established the sulfoximine functionality as a valid transition state mimetic (TSM) in the HIV-1 protease inhibitors (PI) design and have id