1224597-15-2Relevant articles and documents
New xanthate-based radical cyclization onto alkynes
El Kaim, Laurent,Grimaud, Laurence,Miranda, Luis D.,Vieu, Emilie,Cano-Herrera, M.-Angeles,Perez-Labrada, Karel
, p. 2489 - 2491 (2010)
To bypass the failure of radical cyclization involving a xanthate transfer on alkynes, a new reductive cyclization strategy has been completed with the use of a stoichiometric amount of dilauroyl peroxide in isopropanol. When the starting xanthates are prepared via a Ugi 4-component reaction with propargylamine, exomethylene lactams are formed in good yields. The Royal Society of Chemistry.