1224601-73-3Relevant academic research and scientific papers
Total synthesis of the phytotoxic stagonolides A and B
Prabhakar, Peddikotla,Rajaram, Singanaboina,Reddy, Dorigondla Kumar,Shekar, Vanam,Venkateswarlu, Yenamandra
, p. 216 - 221 (2010)
The chemo-enzymatic and covergent synthesis of stagonolide B and the synthesis of stagonolide A, a phytotoxic 10-membered lactone have been achieved starting from d-ribose with overall yields of 25% and 8.7%, respectively. The synthesis contained simple steps in developing three centers' key intermediates, namely the enzymatic (Novozyme-435) resolution of a propargylic alcohol followed by macrolactonization and RCM.
