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1224606-06-7

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Product FOB Price Min.Order Supply Ability Supplier
DLin-MC3-DMA
Cas No: 1224606-06-7
No Data 10 Gram 1000 Gram/Day AVT(Shanghai) Pharmaceutical Tech CO. Ltd. Contact Supplier
D-Lin-MC3-DMA
Cas No: 1224606-06-7
No Data No Data Metric Ton/Day Beijing Jin Ming Biotechnology Co., Ltd. Contact Supplier
DLin-M-C3-DMADLin-M-C3-DMA manufacturer/supplier
Cas No: 1224606-06-7
No Data 1 Gram 1000 Metric Ton/Month Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd Contact Supplier
D-Lin-MC3-DMA CAS:1224606-06-7 DLin-M-C3-DMA
Cas No: 1224606-06-7
USD $ 100.0-100.0 / Gram 1 Gram 10 Kilogram/Month Shaanxi Greenyo Biotech Co., Ltd. Contact Supplier
CAS:1224606-06-7
Cas No: 1224606-06-7
No Data 10 Gram 500 Kilogram/Week Zibo Hangyu Import&Export Co., Ltd Contact Supplier
Hot sell DLin-M-C3-DMA in stock with good quality
Cas No: 1224606-06-7
No Data No Data Metric Ton/Day Hebei Xixun Trading Co.,Ltd Contact Supplier
DLin-MC3-DMA
Cas No: 1224606-06-7
No Data 1 Gram 1-100 Metric Ton/Month CHANGCHUN WEIERSI IMPORT AND EXPORT TRADE CO.,LTD Contact Supplier
D-Lin-MC3-DMA
Cas No: 1224606-06-7
No Data 1 Milligram 5 Xiamen Jenny Chemical Technology Co., Ltd. Contact Supplier
D-Lin-MC3-DMA (MC3)
Cas No: 1224606-06-7
No Data 1 Gram 10 Metric Ton/Month Zibo Dorne chemical technology co. LTD Contact Supplier
DLin-M-C3-DMA
Cas No: 1224606-06-7
No Data 1 Kilogram 100 Kilogram/Day HANGZHOU CLAP TECHNOLOGY CO,.LTD Contact Supplier

1224606-06-7 Usage

Description

D-Lin-MC3-DMA (MC3, DLin-MC3-DMA) is a potent and ionizable cationic lipid. D-Lin-MC3-DMA is used for delivery of siRNA in vivo.? DLin-MC3-DMA, or (6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate , is one of the most utilized cationic lipids that is used for making Lipid Nano-Particles (LNPs). These lipids, can form nanoparticles that can encapsulate and deliver siRNA, mRNA, DNA or small molecules into the cytoplasm and represent the most advanced delivery platforms for systemic administration of active molecules.

Biological Activity

DLin-MC3-DMA is an ionizable lipid used in combination with other lipids for encapsulation of RNA and DNA into lipid nanoparticles (LNPs). Administration of DLin-MC3-DMA based LNPs have delivered siRNA and reduced Factor VII levels in mice. Delivery of BCR-ABL siRNA reduced leukemic burden in a mouse model of chronic myeloid leukemia (CML).
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