1224619-94-6

Basic information

• Product Name: 3-acetyl-1-(2-propen-1-yl)-2-Pyrrolidinone
• Synonyms: 3-acetyl-1-(2-propen-1-yl)-2-Pyrrolidinone
• CAS NO: 1224619-94-6
• Molecular Formula: C9H13NO2
• Molecular Weight: 167.20502
• Mol File: 1224619-94-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-acetyl-1-(2-propen-1-yl)-2-Pyrrolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-acetyl-1-(2-propen-1-yl)-2-Pyrrolidinone(1224619-94-6)
• EPA Substance Registry System: 3-acetyl-1-(2-propen-1-yl)-2-Pyrrolidinone(1224619-94-6)

Safety Data

• Hazardous Substances Data: 1224619-94-6(Hazardous Substances Data)

Upstream product

• 2687-97-0 1-allyl-2-pyrrolidinone 
• 79-20-9 acetic acid methyl ester 

Relevant articles and documents

Synthesis of spirocyclic carbazole- and acridine-lactams

Spirocyclic carbazole- and acridine-lactams were prepared by Fischer-indole or Friedlaender-quinoline synthesis starting from spirocyclic ketones with a lactam ring. All annulation products were obtained as mixtures of separable regioisomers, which differ only in the position of one methyl group. The starting materials were prepared from 2-pyrrolidone and 2-piperidone by a sequence of protection (by N-allylation), α-acylation, iron-catalyzed Michael reaction followed by Robinson-annulation, palladium-catalyzed N-deprotection and catalytic hydrogenation. The overall yields of this six-step sequence are 13 and 17%, respectively, and the racemic ketones are obtained as single diastereoisomers.