1224629-03-1 Usage
General Description
5-Bromo-1-fluoro-3-methyl-2-nitro-benzene is a compound with the chemical formula C7H5BrFNO2. It is a substituted nitrobenzene derivative that consists of a benzene ring with a bromine, fluorine, methyl, and nitro group attached to it. 5-Bromo-1-fluoro-3-methyl-2-nitro-benzene is commonly used in organic synthesis and pharmaceutical research as a building block for the preparation of various pharmaceutical drugs and agrochemicals. It is also used as an intermediate in the manufacturing of dyes, pigments, and other organic compounds. Due to its versatile reactivity and structural diversity, 5-Bromo-1-fluoro-3-methyl-2-nitro-benzene serves as a valuable synthetic precursor in the production of a wide range of chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 1224629-03-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,4,6,2 and 9 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1224629-03:
(9*1)+(8*2)+(7*2)+(6*4)+(5*6)+(4*2)+(3*9)+(2*0)+(1*3)=131
131 % 10 = 1
So 1224629-03-1 is a valid CAS Registry Number.
1224629-03-1Relevant articles and documents
Two-step, regioselective, multigram-scale synthesis of 2-(trifluoromethyl)indoles from 2-nitrotoluenes
Walewska-Królikiewicz, Magdalena,Wilk, Bogdan,Kwast, Andrzej,Wróbel, Zbigniew
supporting information, (2021/11/22)
The acylation of 2-nitrotoluenes using ethyl trifluoroacetate, one of the least expensive sources of a trifluoromethyl group, produces intermediate 2-nitrobenzyl trifluoromethyl ketones which, without the need for isolation, are cyclized under the action of Zn/AcOH providing 2-(trifluoromethyl)indoles unsubstituted at the C3 position. The developed method avoids the use of expensive catalysts and harsh reaction conditions. The method is readily scalable without a significant decrease in performance upon going from 10- to 250-mmol scale.
