1224714-00-4

Basic information

• Product Name: (E)-4-(3,5-dimethoxystyryl)-N-methylaniline
• Synonyms: (E)-4-(3,5-dimethoxystyryl)-N-methylaniline
• CAS NO: 1224714-00-4
• Molecular Weight: 269.343
• Mol File: 1224714-00-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-4-(3,5-dimethoxystyryl)-N-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-(3,5-dimethoxystyryl)-N-methylaniline(1224714-00-4)
• EPA Substance Registry System: (E)-4-(3,5-dimethoxystyryl)-N-methylaniline(1224714-00-4)

Safety Data

• Hazardous Substances Data: 1224714-00-4(Hazardous Substances Data)

Upstream product

• 556-21-8 4-(methylamino)benzaldehyde 
• 108957-75-1 diethyl 3,5-dimethoxybenzylphosphonate 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 705-76-0 3,5-dimethoxybenzyl alcohol 

Downstream Products

• 1415604-94-2 C₁₅H₁₅NO₂ 

Relevant articles and documents

Design, synthesis, and evaluation of resveratrol derivatives as Ass1-42 aggregation inhibitors, antioxidants, and neuroprotective agents

A series of novel resveratrol derivatives were designed, synthesised and evaluated as potential therapeutic agents for the treatment of Alzheimer's disease. Among these compounds, compound 7l, (E)-5-(4-(isopropylamino)styryl) benzene-1,3-diol, exhibited potent ss-amyloid aggregation inhibition activity, which was confirmed by a ThT fluorescence assay (71.65% at 20 μM) and transmission electron microscopy (TEM). Compound 7l also exhibited good antioxidant activity (4.12 Trolox equivalents in an oxygen radical absorbance capacity assay and a 37% reduction in reactive oxygen species in cells at 10 μM). The cytotoxicity analysis of compounds 7f, 7i, 7j and 7l indicated that these compounds have lower toxicities than resveratrol at 60 μM.