1224741-75-6

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 6315-89-5 3,4-dimethoxyaniline 

Downstream Products

• 1185907-11-2 [Cu(C₁₂H₆N₂(C₆H₃(CH₃)2)2)(4,4'-bipyridine)(PF₆)]*(1,2-dichlorobenzene) 
• 1224741-95-0 cis-(N,N-bis(diphenylphosphino)-3,4-dimethoxyaniline)palladium(II) chloride 
• 1224741-91-6 cis-(N,N-bis(diphenylphosphino)-3,4-dimethoxyaniline)platinum(II) chloride 
• 1224741-79-0 N,N-bis(diphenyloxophosphino)-3,4-dimethoxyaniline 
• 1224741-83-6 N,N-bis(diphenylthiophosphino)-3,4-dimethoxyaniline 
• 1224741-87-0 N,N-bis(diphenylselenophosphino)-3,4-dimethoxyaniline 

Relevant academic research and scientific papers

Synthesis and characterization of ether-derivatized aminophosphines and their application in C-C coupling reactions

Four new bis(phosphino)amine ligands (Ph2P)2N-C6H3-R, where R = 3,5-OMe (1), 2,5-OMe (2), 2,4-OMe (3) or 3,4-OMe (4), were prepared via aminolysis of the corresponding dimethoxyanilines with 2 equiv. of diphenylphosphine chloride in the presence of triethyl amine. Oxidation of these ligands with aqueous H2O2, elemental S8 or Se powder afforded the corresponding chalcogen oxides 1a-4a, sulfides 1b-4b and selenides 1c-4c in good yields. Reaction of 1-4 with [MCl2(cod)] (M = Pt, Pd; cod = cycloocta-1,5-diene) in equimolar ratios afforded cis-[MCl2{(Ph2P)2N-C6H3-R}] (M = Pt; R = 3,5-OMe 1d, R = 2,5-OMe 2d, R = 2,4-OMe 3d, and R = 3,4-OMe 4d. M = Pd; R = 3,5-OMe 1e, R = 2,5-OMe 2e, R = 2,4-OMe 3e, and R = 3,4-OMe 4e). Similarly, reaction of [Cu(CH3CN)4]PF6 with the 1-4 in 1:2 ratio gave [Cu{(Ph2P)2N-C6H3-R}2]PF6 (R = 3,5-OMe 1f, 2,5-OMe 2f, 2,4-OMe 3f and 3,4-OMe 4f). All new compounds were fully characterized by spectroscopy and elemental analysis and the molecular structures of seven representative compounds were determined by single-crystal X-ray crystallography. In addition, the palladium complexes were investigated as pre-catalysts in C-C coupling reactions.