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CAS

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1224846-01-8

MK-3697 is an experimental chemical compound being investigated for its potential therapeutic applications, particularly in the treatment of insomnia and other sleep-related disorders. As an orexin receptor antagonist, it functions by blocking orexin, a neurotransmitter that affects wakefulness, arousal, and appetite, making it a promising candidate for promoting sleep. However, MK-3697 is still in the research phase and must undergo extensive clinical trials to evaluate its efficacy, potential side effects, and appropriate dosages before it can be considered for regulatory approval.

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  • 1224846-01-8 Structure

  • Basic information

    1. Product Name: MK-3697
    2. Synonyms: N-[(5,6-Dimethoxy-2-pyridinyl)methyl]-5'-methyl-5-(2-thiazolyl)-[2,3'-bipyridine]-4-carboxamide;MK-3697;N-((5,6-diMethoxypyridin-2-yl)Methyl)-5'-Methyl-5-(thiazol-2-yl)-[2,3'-bipyridine]-4-carboxaMide;Mk3697/Mk-3697;N-[(5,6-diMethoxypyridin-2-yl)Methyl]-5'-Methyl-5-(1,3-thiazol-2-yl)-2,3'-bipyridine-4-carboxaMide;MK-3697 , CID 46190695
    3. CAS NO:1224846-01-8
    4. Molecular Formula: C23H21N5O3S
    5. Molecular Weight: 447.50954
    6. EINECS: N/A
    7. Product Categories: Inhibitors
    8. Mol File: 1224846-01-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: MK-3697(CAS DataBase Reference)
    10. NIST Chemistry Reference: MK-3697(1224846-01-8)
    11. EPA Substance Registry System: MK-3697(1224846-01-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1224846-01-8(Hazardous Substances Data)

1224846-01-8 Usage

Uses

Used in Pharmaceutical Industry:
MK-3697 is used as a therapeutic agent for the treatment of insomnia and other sleep-related disorders. Its application is based on its ability to block orexin receptors, which are involved in regulating wakefulness and arousal, potentially leading to improved sleep quality and duration.
Used in Clinical Research:
MK-3697 is used as a subject of investigation in clinical trials to determine its efficacy, safety, and optimal dosages. These trials are essential for understanding the compound's potential benefits and risks, as well as for guiding its development as a pharmaceutical product.

Check Digit Verification of cas no

The CAS Registry Mumber 1224846-01-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,4,8,4 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1224846-01:
(9*1)+(8*2)+(7*2)+(6*4)+(5*8)+(4*4)+(3*6)+(2*0)+(1*1)=138
138 % 10 = 8
So 1224846-01-8 is a valid CAS Registry Number.

1224846-01-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[(5,6-dimethoxypyridin-2-yl)methyl]-5'-methyl-5-(1,3-thiazol-2-yl)-2,3'-bipyridine-4-carboxamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1224846-01-8 SDS

1224846-01-8Downstream Products

1224846-01-8Relevant articles and documents

ISONICOTINAMIDE OREXIN RECEPTOR ANTAGONISTS

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Page/Page column 53, (2010/05/14)

The present invention is directed to isonicotinamide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. Th

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