1224883-59-3

Upstream product

• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 
• 104-15-4 toluene-4-sulfonic acid 

Downstream Products

• 1345694-89-4 C₁₅H₁₃F₃O₃ 
• 1345694-81-6 C₁₇H₁₇F₃O₃ 
• 1224883-68-4 1-(4-(trifluoromethyl)phenyl)cyclopropan-1-ol 
• 1224883-92-4 1-(4-trifluoromethylphenyl)-5-hexen-1-one 

Relevant academic research and scientific papers

Diastereoselective Alkene Hydroesterification Enabling the Synthesis of Chiral Fused Bicyclic Lactones

Palladium-catalysed diastereoselective hydroesterification of alkenes assisted by the coordinative hydroxyl group in the substrate afforded a variety of chiral γ-butyrolactones bearing two stereocenters. Employing the carbonylation-lactonization products as the key intermediates, the route from the alkenes with single chiral center to chiral THF-fused bicyclic γ-lactones containing three stereocenters was developed.

Catalytic, asymmetric, interrupted Feist-Benary reactions of α-tosyloxyacetophenones

A new variant of the Interrupted Feist-Benary (IFB) reaction uses α-tosyloxyacetophenones as electrophiles and proceeds in good yields and excellent enantioselectivities.