1224955-25-2Relevant academic research and scientific papers
Cu(OAc)2-Mediated Cascade Annulation of Diarylalkyne Sulfonamides through Dual C-N Bond Formation: Synthesis of 5,10-Dihydroindolo[3,2-b]indoles
Yu, Junchao,Zhang-Negrerie, Daisy,Du, Yunfei
, p. 3322 - 3325 (2016)
An unusual cascade reaction featuring annulation of diarylalkyne sulfonamides to form 5,10-dihydroindolo[3,2-b]indoles has been realized with Cu(OAc)2 as the sole oxidant. This unprecedented process encompasses two sequential C-N bond formation
Pt(IV)-catalyzed hydroamination triggered cyclization: A strategy to fused pyrrolo[1,2- a ]quinoxalines, Indolo[1,2- a ]quinoxalines, and Indolo[3,2- c ]quinolines
Patil, Nitin T.,Kavthe, Rahul D.,Shinde, Valmik S.,Sridhar, Balasubramanian
supporting information; experimental part, p. 3371 - 3380 (2010/07/02)
A PtCl4-catalyzed hydroamination-triggered cyclization strategy to access biologically interesting N-containing heterocycles such as pyrrolo[1,2-a]quinoxalines, indolo[1,2-a]quinoxalines, and indolo[3,2-c] quinolines is described. The reaction makes use of aminoaromatics such as 1-(2-aminophenyl)pyrroles, N-(2-aminophenyl)indoles, 2-(2-aminophenyl)indoles, and alkynes having a tethered hydroxyl group. Mechanistically, the reaction is very appealing since it involves multiple catalytic cycles catalyzed by a single metal catalyst PtCl4. We observed a remarkable enhancement of the rate when reactions were run under microwave-assisted conditions.
