1224967-99-0Relevant academic research and scientific papers
Intramolecular aldol reaction of N-Acylated (2-Aminophenyl)-α- oxoacetic Acids: Rapid access to Tri- and tetracyclic 1,2-dihydroquinolin-2(1 H)-ones
Hellal, Malik,Cuny, Gregory D.
supporting information; experimental part, p. 3465 - 3468 (2010/08/07)
A four-step synthesis of tri- and tetracyclic 1,2-dihydroquinolin-2(1H)- ones via acylation of various substituted isatins with readily available N-Boc-protected aminoacids followed by an intramolecular aldol reaction and cyclization has been developed. The final products were obtained in moderate to excellent overall yields.
