1,4,6-Estratriene-3,17-dione, also known as estradiol, is a naturally occurring steroid hormone and the most potent form of estrogen. It plays a crucial role in the development of female secondary sexual characteristics, regulation of the menstrual cycle, and maintenance of pregnancy. Structurally, estradiol consists of a steroid nucleus with three hydroxyl groups at the 3rd, 17th, and 3rd positions, and a double bond between the 1st and 2nd carbon atoms, as well as between the 4th and 5th carbon atoms. This hormone is synthesized primarily in the ovaries, with smaller amounts produced in the adrenal glands and fat cells. Estradiol is essential for bone health, cardiovascular function, and cognitive performance, and it has various therapeutic applications, such as hormone replacement therapy and treatment of certain conditions like menopause and osteoporosis.
The CAS Registry Mumber 1225-04-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,2 and 5 respectively; the second part has 2 digits, 0 and 4 respectively. Calculate Digit Verification of CAS Registry Number 1225-04: (6*1)+(5*2)+(4*2)+(3*5)+(2*0)+(1*4)=43 43 % 10 = 3 So 1225-04-3 is a valid CAS Registry Number.