1225-76-9

Basic information

• Product Name: 1-(4-nitrophenyl)-5-phenyl-1H-1,2,3-triazole
• Synonyms: 1-(4-nitrophenyl)-5-phenyl-1H-1,2,3-triazole
• CAS NO: 1225-76-9
• Molecular Weight: 266.259
• Mol File: 1225-76-9.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1-(4-nitrophenyl)-5-phenyl-1H-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-nitrophenyl)-5-phenyl-1H-1,2,3-triazole(1225-76-9)
• EPA Substance Registry System: 1-(4-nitrophenyl)-5-phenyl-1H-1,2,3-triazole(1225-76-9)

Safety Data

• Hazardous Substances Data: 1225-76-9(Hazardous Substances Data)

Upstream product

• 10480-11-2 1-(4-nitrophenyl)-5-phenyl-Δ²-1,2,3-triazoline 
• 1236-33-5 1-(4-nitrophenyl)-5-phenyl-1H-1,2,3-triazole-4-carboxylic acid 
• 1516-60-5 4-nitrophenyl azide 
• 536-74-3 phenylacetylene 
• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 100-01-6 4-nitro-aniline 
• 588-72-7 [(E)-2-bromoethenyl]benzene 
• 591-50-4 iodobenzene 
• 1204-91-7 1-(4-nitrophenyl)-1H-1,2,3-triazole 
• 621-82-9 Cinnamic acid 

Downstream Products

• 15966-68-4 1-(4-Aminophenyl)-5-phenyl-1,2,3-triazole 
• 84292-60-4 2-[4-(5-Phenyl-[1,2,3]triazol-1-yl)-phenoxy]-butyric acid 
• 84292-47-7 1-(4-Hydroxyphenyl)-5-phenyl-1,2,3-triazole 
• 1083316-52-2 3-phenyl-5-(5-phenyl-1H-1,2,3-triazol-1-yl)-2,1-benzisoxazole 

Relevant articles and documents

Transition-metal-free regioselective construction of 1,5-diaryl-1,2,3-triazoles through dehydrative cycloaddition of alcohols with aryl azides mediated by SO2F2

A novel, simple and practical method for mild, efficient, cost-effective and regioselective synthesis of highly valuable 1,5-diaryl-1,2,3-triazoles was achieved through dehydrative annulation of readily available alcohols with aryl azides. The reaction proceeded at room temperature, without any metal catalysts, exhibiting excellent compatibility to a large variety of functional groups (>50 examples), resulting in up to quantitative yields. 2019

Design and applications of new phosphine-free tetradentate Pd-catalyst: Regioselective C–H activation on 1-substituted 1,2,3-triazoles and indoles(NH-Free)

This article describes the synthesis of a new phosphine free tetradentate Pd catalyst using dl-2,3-diaminopropionic acid. The complex was characterized by Mass, IR, and 1H NMR. The catalyst is air stable at room temperature and non-hygroscopic. Application of this new catalyst to regioselective C–H activation on 1-substituted 1,2,3-triazole and indoles with aryl iodides to get corresponding C-5 and C-2 arylated products with satisfactory yields. All the products were characterized by spectroscopic studies.

Base-mediated reaction of vinyl bromides with aryl azides: One-pot synthesis of 1,5-disubstituted 1,2,3-triazoles

A one-pot base-mediated reaction of azides and β- or α-vinyl bromides has been reported. The effects of bases and solvents have been investigated in the process. A variety of 1,5-disubstituted triazoles were prepared in low to good yields. Further studies reveal that the corresponding alkynes were produced as intermediates via elimination reaction. Under the same reaction conditions, the reactions of alkyl alkynes with phenyl azide would give 1,5-disubstituted 1,2,3-triazoles.