122502-60-7Relevant academic research and scientific papers
THE SYNTHESIS OF 2,3-DISUBSTITUTED CYCLOPENTENONES USING THE RAMBERG-BAECKLUND REACTION IN CONJUNCTION WITH ORGANOCOPPER CHEMISTRY
Casy, Guy,Taylor, Richard J. K.
, p. 455 - 466 (1989)
An improved synthetic procedure is described for the preparation of 2,3-dialkylated 2,3-dihydrothiin-4-ones using organocopper chemistry.The utility of these, and the corresponding saturated compounds for the synthesis of Δ3- and Δ2-2,3-disubstituted cyclopentenones via the Ramberg-Baecklund reaction is discussed.The application of this methodology to a formal total synthesis of the antimicrobial natural product tetrahydrodicranenone B is described.
