122503-09-7Relevant articles and documents
Synthesis and cytotoxicity activity of novel benzotrizolyl methyl[1,2,4-triazolo][3,4-b]thiadiazinyl substituted chromene 2-ones
Yakaiah,Durgaprasad,Rao, A. K. S. Bhujanga,Rani, P. Baby,Awantika,Buchappa,Aparna
, p. 1381 - 1384 (2016/04/08)
The biological importance of the coumarins and triazolothiadiazines, prompted as to synthesize a series of novel benzotrizolyl methyl[1,2,4-triazolo][3,4-b]thiadiazinyl substituted chromene 2-ones applying simple experimental conditions with good yields. All the synthesized molecules were well characterized by physical, analytical and spectroscopic techniques. The novel synthesized molecules 5(a-k) were screened for the anticancer activity and some of the molecules exhibited moderate to good activity in vitro.