1225031-07-1

Basic information

• Product Name: 1-(2,6-difluorobenzyl)-4-methylbenzene
• Synonyms: 1-(2,6-difluorobenzyl)-4-methylbenzene
• CAS NO: 1225031-07-1
• Molecular Weight: 218.246
• Mol File: 1225031-07-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(2,6-difluorobenzyl)-4-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,6-difluorobenzyl)-4-methylbenzene(1225031-07-1)
• EPA Substance Registry System: 1-(2,6-difluorobenzyl)-4-methylbenzene(1225031-07-1)

Safety Data

• Hazardous Substances Data: 1225031-07-1(Hazardous Substances Data)

Upstream product

• 38361-37-4 1-chloro-2,6-difluorobenzene 
• 104-82-5 4-Methylbenzyl chloride 
• 85118-00-9 2,6-Difluorobenzyl bromide 
• 5720-05-8 4-methylphenylboronic acid 

Relevant articles and documents

Palladium-Catalyzed Decarboxylation of Benzyl Fluorobenzoates

The decarboxylation of benzyl fluorobenzoates has been developed by using the palladium catalyst prepared in situ from Pd(η 3 -allyl)Cp and bulky monophosphine ligand XPhos. The catalytic reaction afforded a range of fluorinated diarylmethanes in good yields with broad functional-group compatibility. The substrates were readily synthesized by condensation of the corresponding benzoic acid with benzyl alcohol. Therefore, the transformation is formally regarded as a cross-coupling reaction between fluorine-containing benzoic acids and benzyl alcohols.

Benzothiazolin-2-ylidene and azole mixed-ligand complexes of palladium

A series of mixed-ligand, mononuclear complexes trans[PdX 2(NSHC)(azole)] [NSHC = N,S-heterocyclic carbene; azole = imidazole, l-(2,4,6-trimethylphenyl)-1H-imidazole, benzimidazole, benzothiazole and benzoxazole] have been prepared and characterised by X-ray single-crystal diffrac-tion. These complexes catalyse the sp2-sp3 cross-coupling of fluoroaryl halides with arylboronic acid to give diarylmethanes with good yields and high turnovers, Wiley-VCH Verlag GmbH & Co. KGaA.