1225375-80-3Relevant academic research and scientific papers
Enantioselective chemoenzymatic synthesis of cis- and trans -2,5-disubstituted morpholines
Ritzen, Bas,Hoekman, Steven,Verdasco, Elena Duran,Van Delft, Floris L.,Rutjes, Floris P. J. T.
supporting information; experimental part, p. 3461 - 3464 (2010/08/19)
A versatile synthesis of enantiomerically pure cis- and trans-2,5-disubstituted morpholines is described. Hydroxynitrile lyase-mediated cyanide addition onto aldehydes provided cyanohydrins in virtually quantitative yield and excellent enantioselectivity.
