122552-70-9

Basic information

• Product Name: (E)-(3R,3aR,5S,6aR,9aS)-3-(tert-Butyl-diphenyl-silanyloxy)-5-hydroxy-9a-methyl-4-methylene-3,3a,4,5,6,6a,7,8,9,9a-decahydro-2H-dicyclopenta[a,d]cycloocten-1-one
• Synonyms: (E)-(3R,3aR,5S,6aR,9aS)-3-(tert-Butyl-diphenyl-silanyloxy)-5-hydroxy-9a-methyl-4-methylene-3,3a,4,5,6,6a,7,8,9,9a-decahydro-2H-dicyclopenta[a,d]cycloocten-1-one
• CAS NO: 122552-70-9
• Molecular Weight: 500.753
• Mol File: 122552-70-9.mol

Chemical Properties

• CAS DataBase Reference: (E)-(3R,3aR,5S,6aR,9aS)-3-(tert-Butyl-diphenyl-silanyloxy)-5-hydroxy-9a-methyl-4-methylene-3,3a,4,5,6,6a,7,8,9,9a-decahydro-2H-dicyclopenta[a,d]cycloocten-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(3R,3aR,5S,6aR,9aS)-3-(tert-Butyl-diphenyl-silanyloxy)-5-hydroxy-9a-methyl-4-methylene-3,3a,4,5,6,6a,7,8,9,9a-decahydro-2H-dicyclopenta[a,d]cycloocten-1-one(122552-70-9)
• EPA Substance Registry System: (E)-(3R,3aR,5S,6aR,9aS)-3-(tert-Butyl-diphenyl-silanyloxy)-5-hydroxy-9a-methyl-4-methylene-3,3a,4,5,6,6a,7,8,9,9a-decahydro-2H-dicyclopenta[a,d]cycloocten-1-one(122552-70-9)

Safety Data

• Hazardous Substances Data: 122552-70-9(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 122552-76-5 ((1S,2R)-2-{2-[(4-Methoxy-phenyl)-diphenyl-methoxy]-ethyl}-1-methyl-cyclopentyl)-methanol 
• 122552-67-4 (4R)-(+)-2-bromo-4-[(1,1-dimethylethyl)diphenylsilyloxy]cyclopent-2-en-1-one 
• 107657-42-1 (4R)-(+)-4-[(1,1-dimethylethyl)diphenylsilyloxy]cyclopent-2-en-1-one 
• 98049-46-8 (1'R,2'R)-2-(2'-hydroxymethyl-2'-methyl-3'-methylenecyclopentyl)ethanoic acid 
• 59995-47-0 (R)-(+)-4-hydroxy-2-cyclopentenone 
• 122552-69-6 {(1R,2S)-2-[(2R,3R)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(1-iodo-vinyl)-5-oxo-cyclopent-(E)-ylidenemethyl]-2-methyl-cyclopentyl}-acetaldehyde 
• 122552-75-4 Imidazole-1-carbothioic acid O-((2S,3R)-2-(tert-butyl-diphenyl-silanyloxymethyl)-3-{2-[(4-methoxy-phenyl)-diphenyl-methoxy]-ethyl}-2-methyl-cyclopentyl) ester 
• 122552-65-2 tert-Butyl-((1R,2R)-2-{2-[(4-methoxy-phenyl)-diphenyl-methoxy]-ethyl}-1-methyl-5-methylene-cyclopentylmethoxy)-diphenyl-silane 
• 122552-74-3 (2S,3R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-{2-[(4-methoxy-phenyl)-diphenyl-methoxy]-ethyl}-2-methyl-cyclopentanol 
• 122552-73-2 C₄₂H₅₂O₃Si₂ 
• 122576-94-7 tert-Butyl-((1S,2R)-2-{2-[(4-methoxy-phenyl)-diphenyl-methoxy]-ethyl}-1-methyl-cyclopentylmethoxy)-diphenyl-silane 
• 122552-68-5 C₃₂H₄₉BrO₂Si₃ 
• 122552-66-3 (1S,2R)-2-{2-[(4-Methoxy-phenyl)-diphenyl-methoxy]-ethyl}-1-methyl-cyclopentanecarbaldehyde 

Downstream Products

• 123517-71-5 C₃₂H₄₀O₄Si 
• 122552-71-0 C₃₆H₄₂N₂O₄SSi 
• 122552-80-1 (E)-(1R,3R,3aS,6aR,9aR)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-3-(tert-butyl-diphenyl-silanyloxy)-1,9a-dimethyl-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-dicyclopenta[a,d]cycloocten-1-ol 
• 122576-95-8 (E)-(3R,3aS,6aR,9aR)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-3-(tert-butyl-diphenyl-silanyloxy)-9a-methyl-3,3a,6,6a,7,8,9,9a,10,10a-decahydro-2H-dicyclopenta[a,d]cycloocten-1-one 
• 122552-72-1 (E)-(3R,3aS,6aR,9aR)-3-(tert-Butyl-diphenyl-silanyloxy)-4-hydroxymethyl-9a-methyl-3,3a,6,6a,7,8,9,9a,10,10a-decahydro-2H-dicyclopenta[a,d]cycloocten-1-one 

Relevant articles and documents

SYNTHETIC STUDIES ON OPHIOBOLINS

The tricyclic ketone 14, an ophiobolin analogue lacking only the C-ring side chain, was synthesized in optically active form; the key step was the intramolecular NiCl2/CrCl2 mediated coupling of 10 to yield 11.