1225544-56-8Relevant academic research and scientific papers
Total synthesis of ascididemin via anionic cascade ring closure
Petersen, Ida Nymann,Crestey, Francois,Kristensen, Jesper Langgaard
, p. 9092 - 9094,3 (2020/08/31)
A new and convergent synthesis of ascididemin is presented. Using an anionic cascade ring closure as the key step, this natural product is obtained in 45% overall yield in just 6 steps starting from 2′-fluoroacetophenone. This new approach was extended to the synthesis of a new isomer of ascididemin.
