122556-80-3Relevant articles and documents
N-Hydroxy Amides. Part 6. Synthesis and Spectroscopic Properties of 1-Hydroxypiperazine-2,5-diones
Akiyama, Masayasu,Katoh, Akira,Tsuchiya, Yuko
, p. 235 - 239 (2007/10/02)
1-Hydroxypiperazine-2,5-diones (3a-f) are prepared in good yields, starting with Boc-L-amino acids and N-benzyloxyglycine methyl ester.The rate of cyclisation for N-hydroxy and N-benzyloxydipeptide methyl esters are 38-77 times as large as that of phenyla