1225589-66-1

Basic information

• Product Name: 3-Butynoic acid, 4-(2-aMino-4-fluoro-5-nitrophenyl)-2,2-diMethyl-, phenylMethyl ester
• Synonyms: 3-Butynoic acid, 4-(2-aMino-4-fluoro-5-nitrophenyl)-2,2-diMethyl-, phenylMethyl ester;Benzyl 4-(2-amino-4-fluoro-5-nitrophenyl)-2,2-dimethylbut-3-ynoate
• CAS NO: 1225589-66-1
• Molecular Formula: C₁₉H₁₇FN₂O₄
• Molecular Weight: 356.3476832
• Mol File: 1225589-66-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Butynoic acid, 4-(2-aMino-4-fluoro-5-nitrophenyl)-2,2-diMethyl-, phenylMethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butynoic acid, 4-(2-aMino-4-fluoro-5-nitrophenyl)-2,2-diMethyl-, phenylMethyl ester(1225589-66-1)
• EPA Substance Registry System: 3-Butynoic acid, 4-(2-aMino-4-fluoro-5-nitrophenyl)-2,2-diMethyl-, phenylMethyl ester(1225589-66-1)

Safety Data

• Hazardous Substances Data: 1225589-66-1(Hazardous Substances Data)

Upstream product

• 952664-69-6 2-bromo-5-fluoro-4-nitroaniline 
• 204588-77-2 2,2-dimethyl-3-butynoic acid benzyl ester 

Downstream Products

• 1152311-77-7 benzyl 2-(6-fluoro-5-nitro- 1H-indol-2-yl)-2-methylpropanoate 

Relevant articles and documents

MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ('ABC') transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ('CFTR'). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.