122576-99-2Relevant academic research and scientific papers
Palladium Catalysis in Cephalosporin Chemistry: General Methodology for the Synthesis of Cephem Side Chains
Farina, Vittorio,Baker, Stephen R.,Benigni, Daniel A.,Hauck, Sheila I.,Sapino, Chester
, p. 5833 - 5847 (2007/10/02)
We describe in full the palladium-catalyzed coupling of 3-(triflyloxy)cephems with organotin compounds, leading to the synthesis of 3-alkenyl-, 3-alkynyl-, and 3-arylcephems under exceptionally mild conditions.While this approach was not satisfactory for
PALLADIUM CATALYSIS IN CEPHALOSPORIN CHEMISTRY: A VERSATILE NEW APPROACH TO 3-SUBSTITUTED CEPHEMS
Farina, Vittorio,Baker, Stephen R.,Sapino, Chester
, p. 6043 - 6046 (2007/10/02)
The coupling of 3-triflyloxycephems with unsaturated stannanes proceeds under mild conditions with the use of a palladium (O) catalyst based on the new ligand tri(2-furyl)phosphine
