122592-49-8

Basic information

• Product Name: 2-Propenoic acid, 3-(tetrahydro-2-furanyl)-, methyl ester, (Z)-
• CAS NO: 122592-49-8
• Molecular Formula: C8H12O3
• Molecular Weight: 156.181
• Mol File: 122592-49-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(tetrahydro-2-furanyl)-, methyl ester, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(tetrahydro-2-furanyl)-, methyl ester, (Z)-(122592-49-8)
• EPA Substance Registry System: 2-Propenoic acid, 3-(tetrahydro-2-furanyl)-, methyl ester, (Z)-(122592-49-8)

Safety Data

• Hazardous Substances Data: 122592-49-8(Hazardous Substances Data)

Upstream product

• 7681-84-7 tetrahydrofuran-2-carbaldehyde 
• 88738-78-7 bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 124988-85-8 rac-3-(2-Tetrahydrofuryl)tetrahydro-1-(phenylmethyl)-1H,6H-furo<3,4-c>isoxazol-6-one 
• 124919-04-6 C₁₆H₁₉NO₄ 

Relevant articles and documents

Reductive Cleavage Reaction of γ-Functionalized α,β-Unsaturated Esters and Halomethyls Mediated with Magnesium in Methanol

Reductive cleavage of various types of C-O and C-N bonds tethered to α,β-unsaturated esters and halomethyls was mediated with magnesium in methanol, which provided a facile method for the synthesis of δ-hydroxy or δ-amino β,γ-unsaturated esters and allylic alcohols.Regardless of the geometry (E or Z) of the α,β-unsaturated esters, 1a-b, 5a-c, 11, 13, and 23, the cleavage product obtained was exclusively the E isomer of the corresponding deconjugated hydroxy and amino esters.The steric bias and ring strain of 15, 17, and 21 gave rise to a product mixture of E and Z isomers.

Stereoselective Intramolecular Nitrone Cycloadditions Promoted by an Allylic Stereocenter

A series of intramolecular nitrone cycloadditions to chiral allyl ethers was studied in order to evaluate the influence on the stereochemical outcome exerted by several factors, including the nature of the substituents at the stereocenter and the steric and electronic features of the double bond.A comparison between the stereoselectivity of these reactions and that of related nitrile oxides cycloadditions suggests that they could proceed via similar transition states.