1225959-45-4Relevant academic research and scientific papers
A gold-catalyzed 1,2-acyloxy migration/intramolecular cyclopropanation/ring enlargement cascade: Syntheses of medium-sized heterocycles
Sun, Yin-Wei,Tang, Xiang-Ying,Shi, Min
supporting information, p. 13937 - 13940 (2015/09/07)
The synthesis of medium-sized heterocycles possessing a trans double bond is still a challenge. Herein, gold(I)-catalyzed 1,2-acyloxy migration/intramolecular cyclopropanation/ring enlargement cascade reaction of furans has been developed, providing highly efficient access to ten- and eleven-membered heterocycles with a broad substrate scope under mild reaction conditions. The reaction outcome features high chemoselectivity at the C5-position of furan. Moreover, a trans-double bond was embodied in the medium ring system.
Titanocene(III) chloride mediated reductive cleavage of arylcyclopropyl ketones
Paira,Mandal,Roy
experimental part, p. 573 - 577 (2010/12/25)
Titanocene(III) chloride (Cp2TiCl) mediated cleavage of arylcyclopropyl ketones has been accomplished. Both saturated and β-H eliminated unsaturated aromatic compounds are formed in different ratio depending on the substrate. Ti(III) species has been prepared in situ from commercially available titanocene dichloride (Cp2TiCl2) and zinc dust in THF.
