1226-48-8

Usage

Uses

Used in Organic Synthesis:
2-Nitrophenyl 4-methylbenzenesulfonate is used as a reagent in organic synthesis for the preparation of various compounds. Its versatility in undergoing different chemical transformations makes it a valuable building block in the production of a broad spectrum of organic compounds.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2-nitrophenyl 4-methylbenzenesulfonate is utilized as a key intermediate in the synthesis of pharmaceuticals. It contributes to the development of new drugs by facilitating the creation of complex molecular structures.
Used in Agrochemical Production:
2-Nitrophenyl 4-methylbenzenesulfonate also finds application in the agrochemical sector, where it is used in the synthesis of agrochemicals. Its role in this industry is crucial for the development of effective crop protection products.
Used in Industrial Chemical Manufacturing:
2-nitrophenyl 4-methylbenzenesulfonate is further employed in the manufacturing of industrial chemicals, where it serves as a reagent to produce a variety of chemical products used across different industries.
Used in Chemical Research:
2-Nitrophenyl 4-methylbenzenesulfonate is also used as a research tool in chemical laboratories for modifying and functionalizing organic molecules. Its ability to participate in various chemical reactions makes it instrumental in advancing scientific understanding and the development of new chemical entities.

Upstream product

• 88-75-5 2-hydroxynitrobenzene 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 2436-96-6 1-nitro-2-(2-nitrophenyl)benzene 
• 1239-12-9 2-p-Toluolsulfonyloxy-benzolazocarbonsaeure-ethylester 
• 1239-11-8 2-p-Toluolsulfonyloxy-phenylhydrazincarbonsaeure-ethylester 
• 3749-88-0 2-p-Toluolsulfonyloxy-phenylhydrazin 
• 92854-26-7 Mesoxalylchlorid-2-p-toluolsulfonyloxyphenylhydrazon 
• 94680-77-0 Diethylmesoxalat-2-p-toluolsulfonyloxyphenylhydrazon 
• 93020-43-0 Mesoxalsaeure-2-p-toluolsulfonyloxyphenylhydrazon 
• 49834-35-7 N-<2-(4-Methylphenylsulfonyloxy)phenyl>benzamid 
• 833-50-1 2-phenylbenzo[d]oxazole 
• 953424-12-9 2-[(phenylcarbonothioyl)amino]phenyl 4-methylbenzenesulfonate 
• 104-15-4 toluene-4-sulfonic acid 
• 88-75-5 2-hydroxynitrobenzene 
• 189759-46-4 2-nitro-5-(toluene-4-sulfonylmethyl)phenyl toluene-4-sulfonate 
• 18097-21-7 chlorobis(toluene-4-sulfonyl)methane 

Relevant academic research and scientific papers

Ionic liquid brush as an efficient and reusable heterogeneous catalytic assembly for the tosylation of phenols and alcohols in neat water

A very efficient and reusable heterogeneous ionic liquid brush assembly was developed. The catalyst exhibits high catalytic activity for the tosylation of phenols and alcohols in neat water. Moreover, the catalyst shows outstanding stability and reusability, and it can be simply and effectively recovered and reused five times without noticeable loss of catalytic activity.

DBN hexafluorophosphate salts as convenient sulfonylating and phosphonylating agents

Air-stable N-sulfonyl and N-phosphonyl DBN hexafluorophosphate salts have been synthesised under mild conditions as sulfonylating and phosphonylating agents. These salts are highly efficient in the sulfonylation and phosphonylation of a range of N- and O-nucleophiles to generate sulfonamides, sulfonate esters, phosphoramidates and phosphonate esters in good yields.

Chromatography-Free and Eco-Friendly Synthesis of Aryl Tosylates and Mesylates

Two chromatography-free and eco-friendly protocols have been developed to synthesize aryl tosylates and mesylates by the tosylation and mesylation of the corresponding hydroxyarenes, respectively. These protocols are superior to other known ones regarding

Cs2CO3 catalyzed rapid and efficient conversion of amines into sulfonamides; Alcohols and phenols into sulfonic esters

A simple and efficient method has been developed for the sulfonylation of several amines, alcohols, and phenols by p-toluenesulphonylchloride (p-TsCl) in the presence of catalytic amount of Cs2CO3 at 25C to obtain sulfonamides and sulfonic esters in very good yields. Cs2CO3 has been found to be highly efficient catalyst. Taylor & Francis Group, LLC.

A simple and efficient method for sulfonylation of amines, alcohols and phenols with cupric oxide under mild conditions

Cupric Oxide efficiently catalyzed the synthesis of sulfonamides and sulfonic esters. This method has been applied to a variety of substrates including nucleophilic and sterically-hindered amines, alcohols and phenols with excellent yields of sulfonamides and sulfonic esters. The remarkable selectivity under mild and neutral conditions of this commercially available inexpensive catalyst is an attractive feature of this method.

Iodine-mediated cyclisation of thiobenzamides to produce benzothiazoles and benzoxazoles

Synthesis of benzothiazoles by reaction of iodine with thiobenzamides, which do not possess an ortho alkoxy or ester group, is described. The unlikely synthesis of benzoxazoles from reaction of 2-alkoxythiobenzamides with iodine is also reported.

Ammonolysis of Aryl Toluenesulphonate Esters: Evidence for the Concerted Displacement of the Aryl Oxide Group

Rate constants have been measured for the ammonolysis of aryl toluenesulphonate esters in aqueous solution.The Broensted-type β value of -1.08 coupled with the βeq for the overall reaction indicates a large increase in negative effective charge