1226159-70-1

Upstream product

• 269745-89-3 (5-bromo-thiophen-2-yl)-(3-nitrophenyl)methanone 
• 121-90-4 m-nitrobenzoic acid chloride 

Downstream Products

• 1617505-82-4 (3-amino-phenyl)(5-(3-ethoxy-phenyl)-thiophen-2-yl)methanone 
• 1617505-89-1 N-(3-(5-(3-ethoxyphenyl)-thiophene-2-yl-carbonyl)-phenyl)-4-methoxy-benzenesulfonamide 
• 1617505-88-0 3-cyano-N-(3-(5-(3-ethoxyphenyl)-thiophene-2-yl-carbonyl)phenyl)-benzenesulfonamide 
• 1617505-91-5 N-(3-(5-(3-ethoxyphenyl)-thiophene-2-yl-carbonyl)phenyl)-isophthalamicacid methyl ester 
• 1617505-83-5 N-(3-(5-(3-ethoxyphenyl)-thiophene-2-yl-carbonyl)-phenyl)-C,C,C-trifluoro-methanesulfonamide 
• 1617505-84-6 (5-(3-ethoxyphenyl)-thiophen-2-yl)-(3-isopropylamino-phenyl)methanone 
• 1617505-85-7 1-(3-(5-(3-ethoxyphenyl)-thiophene-2-yl-carbonyl)-phenyl)-3-methyl-thiourea 
• 1617505-86-8 (3-benzylaminophenyl)-(5-(3-ethoxyphenyl)-thiophen-2-yl)-methanone 
• 1617505-92-6 N-(3-(5-(3-ethoxy-phenyl)-thiophene-2-yl-carbonyl)-phenyl)-isophthalamic acid 
• 1617505-87-9 N-(3-(5-(3-ethoxyphenyl)-thiophene-2-yl-carbonyl)-phenyl)-benzenesulfonamide 
• 1617505-90-4 N-(3-(5-(3-ethoxyphenyl)-thiophene-2-yl-carbonyl)-phenyl)-benzamide 

Relevant academic research and scientific papers

Inhibition of 17β-HSD1: SAR of bicyclic substituted hydroxyphenylmethanones and discovery of new potent inhibitors with thioether linker

Estradiol is the most potent estrogen in humans. It is known to be involved in the development and proliferation of estrogen dependent diseases such as breast cancer and endometriosis. The last step of its biosynthesis is catalyzed by 17β-hydroxysteroid d