1226161-12-1

Basic information

• Product Name: 3-(2-fluorophenyl)-2,2-diMethylpropanoic acid
• Synonyms: 3-(2-fluorophenyl)-2,2-diMethylpropanoic acid
• CAS NO: 1226161-12-1
• Molecular Formula: C11H13FO2
• Molecular Weight: 196.2181232
• Mol File: 1226161-12-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(2-fluorophenyl)-2,2-diMethylpropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-fluorophenyl)-2,2-diMethylpropanoic acid(1226161-12-1)
• EPA Substance Registry System: 3-(2-fluorophenyl)-2,2-diMethylpropanoic acid(1226161-12-1)

Safety Data

• Hazardous Substances Data: 1226161-12-1(Hazardous Substances Data)

Upstream product

• 446-48-0 o-fluorobenzyl bromide 

Relevant articles and documents

Sulfoximine assisted Pd(II)-catalyzed bromination and chlorination of primary β-C(sp3)-H bond

S-Methyl-S-2-pyridyl-sulfoximine (MPyS) directed bromination and chlorination of the 1°-β-C(sp3)-H bond of MPyS-N-amides is realized under the influence of N-Br/Cl-phthalimides and a Pd(II)-catalyst. The sequential halogenation and acetoxylation of α-dimethyl MPyS-N-amides constructs highly functionalized α-trisubstituted aliphatic acid derivatives. The MPyS directing group is cleaved from the halogenated products and recovered. (Chemical Equation Presented).