122620-17-1Relevant articles and documents
[3.3.0]Pyrazolodinones: an efficient synthesis of a new class of synthetic antibacterial agents
Ternansky,Draheim
, p. 2805 - 2808 (1990)
A novel synthesis of [3.3.0] fused pyrazolidinones is described. The methodology relies on selective stepwise functionalization of the ring nitrogens of a known pyrazolidinone monocycle. Intramolecular Wadsworth-Horner-Emmons condensation gives rise to the desired bicyclic structure. The compounds prepared from this route have demonstrated potent antibacterial activity in vitro.