122648-58-2

Upstream product

• 122677-51-4 (+/-)-tert-butyl<(1R*,4S*,10R*)-4-<(2-methoxyethoxy)methoxy>bicyclo<7.2.1>dodec-9(12)-en-10-yl>oxydimethylsilane 
• 122648-55-9 (+/-)-(1R*,4S*,10R*)-10-(tert-butyldimethylsiloxy)bicyclo<7.2.1>dodec-9(12)-en-4-ol 
• 122648-57-1 (+/-)-(1R*,4S*,10R*)-4-<(2-methoxyethoxy)methoxy>bicyclo<7.2.1>-dodec-9(12)-en-10-ol 
• 122648-48-0 (+/-)-(1R*,10R*)-10-(tert-butyldimethylsiloxy)bicyclo<7.2.1>dodec-9(12)-en-4-one 
• 5707-04-0 Phenylselenyl chloride 
• 122648-50-4 (+/-)-(1R*,4S*)-4-<(2-methoxyethoxy)methoxy>bicyclo<7.2.1>dodec-9(12)-en-10-one 

Downstream Products

• 122648-51-5 (+/-)-(1R*,4R*,11R*)-4-<(2-methoxyethoxy)methoxy>-11-methyl-11-(phenylselenyl)bicyclo<7.2.1>dodec-9(12)-en-10-one 

Relevant academic research and scientific papers

Application of the anionic oxy-cope rearrangement to stereocontrolled synthesis of the A/B subunit of cytoxic 8,9-seco-ent-kaurenes

Methodology is described for expedient synthesis of the A/B framework of 8,9-seco-ent-kaurenes and for introduction of the 5-methylene-2-cyclopentenone moiety. In the first part of the study, a sequence of only six steps is necessary to convert 2-(hydroxy