1226482-25-2Relevant academic research and scientific papers
Visible-light-promoted iminyl-radical formation from Acyl oximes: A unified approach to pyridines, quinolines, and phenanthridines
Jiang, Heng,An, Xiaode,Tong, Kun,Zheng, Tianyi,Zhang, Yan,Yu, Shouyun
, p. 4055 - 4059 (2015)
A unified strategy involving visible-light-induced iminyl-radical formation has been established for the construction of pyridines, quinolines, and phenanthridines from acyl oximes. With fac-[Ir(ppy)3] as a photoredox catalyst, the acyl oximes were converted by 1 e- reduction into iminyl radical intermediates, which then underwent intramolecular homolytic aromatic substitution (HAS) to give the N-containing arenes. These reactions proceeded with a broad range of substrates at room temperature in high yield. This strategy of visible-light-induced iminyl-radical formation was successfully applied to a five-step concise synthesis of benzo[c]phenanthridine alkaloids.
Efficient and Reusable Pb(II) Metal–Organic Framework for Knoevenagel Condensation
Almá?i, Miroslav,Zeleňák, Vladimír,Opanasenko, Maksym V.,?ejka, Ji?í
, p. 2263 - 2273 (2018/07/05)
A microporous lead–organic framework {[Pb4(μ8-MTB)2(H2O)4]·5DMF·H2O}n (MTB = methanetetrabenzoate, DMF = N,N′-dimethylformamide) was synthesized and studied as a catalyst in Knoevenagel condensation reactions. The framework is built from tetranuclear [Pb4(μ3-COO)(μ2-COO)6(COO)(H2O)4] clusters and exhibits a 3D structure, with repeated 1D jar-like cavities with sizes about 14.98 × 7.88 and 14.98 × 13.17??2 and BET specific surface area of 980?m2?g?1. To obtain open framework with unsaturated Pb(II) sites needed for catalysis, the thermal activation of the solvent exchanged sample was performed (DMF was exchanged by EtOH). The activated compound was tested in Knoevenagel condensation of bulky aldehydes and active methylene compounds at different temperatures. Excellent catalytic conversion and selectivity in condensation of small-sized aldehydes with malononitrile was observed, which indicates that the opened Pb(II) sites play a significant role in the heterogeneous catalytic process. Leaching test confirmed the stability of the catalyst in catalytic reactions. Moreover, the compound displayed good recyclability after several reuses without significant decrease in the original catalytic activity. Graphical Abstract: Novel Pb(II) metal–organic framework was tested in Knoevenagel condensation. The catalyst showed excellent catalytic conversion, selectivity and recyclability. Aldehydes with lower kinetic diameter demonstrated high conversions and yields. Catalyst is less efficient for condensation of larger aromatic aldehydes. [Figure not available: see fulltext.].
A novel nickel metal-organic framework with fluorite-like structure: Gas adsorption properties and catalytic activity in Knoevenagel condensation
Almasi, Miroslav,Zelenak, Vladimir,Opanasenko, Maksym,Cejka, Jiri
, p. 3730 - 3738 (2014/03/21)
A new non-interpenetrating 3D metal-organic framework {[Ni 4(μ6-MTB)2(μ2-H 2O)4(H2O)4] ·10DMF·11H2O}n (DMF = N,N′- dimethylformamide) built from
