122652-29-3

Upstream product

• 6332-22-5 1-(4-bromophenyl)-3-(4-chlorophenyl)prop-2-en-1-one 
• 109-77-3 malononitrile 

Downstream Products

• 400031-76-7 2-amino-6-(4-bromo-phenyl)-4-(4-chloro-phenyl)-nicotinamide 
• 693810-12-7 7-(4-bromo-phenyl)-5-(4-chloro-phenyl)-4-imino-3-(2-methoxy-phenyl)-3,4-dihydro-1H-pyrido[2,3-d]pyrimidine-2-thione 
• 693810-04-7 7-(4-bromo-phenyl)-3-(3-chloro-phenyl)-5-(4-chloro-phenyl)-4-imino-3,4-dihydro-1H-pyrido[2,3-d]pyrimidin-2-one 
• 400031-96-1 7-(4-bromo-phenyl)-5-(4-chloro-phenyl)-3-(4-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 
• 1370256-07-7 1-[6-(4-bromophenyl)-4-(4-chlorophenyl)-3-cyano-pyridin-2-yl]-5-oxopyrrolidine-3-carboxylic acid 

Relevant academic research and scientific papers

Synthesis and antimicrobial screening of some new 4-imino-3,5,7- trisubstituted pyrido[2,3-d]pyrimidines and their ribofuranosides as potential chemotherapeutic agents

Some new nucleosides, viz. 4-imino-3,5,7-trisubstituted-1-(2′, 3′,5′-tri-O-benzyl-β-D-ribofuranosyl)pyrido[2,3-d]pyrimidin / e-2(1H)-ones / thiones(VII/VIII), have been synthesized by condensation of trimethylsilyl derivatives of 4-imino-3,5,7-trisubstitu

Synthesis of some 2-thioxopyrido[2,3-d]pyrimidine ribofuranosides and their antimicrobial activity

2-Thioxo-3,5,7-trisubstituted-1-[2′,3′.5′-tri-O-benzoyl-β -D-ribofuranosyl]pyrido[2,3-d]pyri midin-4(IH)-ones have been prepared by the condensation of trimethylsilyl derivative of 2-thioxo-3,5,7-trisubstituted pyrido[2,3-d]pyrimidin-4(IH)-ones with β-D-ribofuranose 1-acetate-2,3,5-tribenzoate in 65%-78% yield. The structure of the synthesized ribofuranosides and their precursors have been established by IR. 1H NMR and elemental analysis. These derivatives have been screened for their antimicrobial activity.