122663-18-7Relevant articles and documents
Renin Inhibitors Containing Conformationally Restricted P1-P1' Dipeptide Mimetics
Williams, Peter D.,Perlow, Debra S.,Payne, Linda S.,Holloway, M. Katharine,Siegl, Peter K. S.,et al.
, p. 887 - 900 (2007/10/02)
A series of renin inhibitors containing lactam-bridged P1-P1' dipeptide mimetics based on the ACHPA (4(S)-amino-5-cyclohexyl-3(S)-hydroxypentanoic acid) design was studied.The inhibitors were obtained by aldol addition of various lac