1226795-30-7

Upstream product

• 813-19-4 bis(tri-n-butyltin) 
• 566169-96-8 6-bromo-2-(4-nitrophenyl)benzo[d]thiazole 
• 23451-95-8 2-amino-5-bromobenzenethiol 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 1226795-25-0 (2-(4-nitrophenyl)benzothiazol-6-yl)(phenyl)iodonium tosylate 
• 566169-97-9 2-(4’-aminophenyl)-6-bromobenzothiazole 
• 1226795-17-0 2-(4'-aminophenyl)-6-⁽¹⁸⁾F-fluorobenzothiazole 

Relevant academic research and scientific papers

FLUORINATED BENZOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND IMAGING AGENT FOR DIAGNOSING ALTZHEIMER'S DISEASE USING THE SAME

The present invention relates to fluorinated benzothiazole derivatives, a preparation method thereof, and an imaging agent for diagnosing Alzheimer's disease using the same, and more particularly to fluorinated benzothiazole derivatives represented by Che

FLUORINATED BENZOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND IMAGING AGENT FOR DIAGNOSING ALTZHEIMER'S DISEASE USING THE SAME

The present invention relates to fluorinated benzothiazole derivatives, a preparation method thereof, and an imaging agent for diagnosing Alzheimer' s disease using the same, and more particularly to fluorinated benzothiazole derivatives represented by Chemical Formula 1, derivatives of Chemical Formula 2 as a starting material for preparation thereof, a preparation method thereof, and an imaging agent for diagnosing Alzheimer's disease using fluorinated benzothiazole derivatives with a strong binding force to beta-amyloid plaque, which is a kind of biomarker for Alzheimer's disease. According to the present invention, fluorine-labeled benzothiazole derivatives, which have been difficult to synthesize by conventional methods, may be obtained by simple processes and the thus-obtained benzothiazole derivatives may be useful in diagnosing the presence and severity of Alzheimer's disease.