1226804-63-2Relevant academic research and scientific papers
An efficient synthesis of 4-chloro-2-pyrrolino[2,3- d ]pyrimidin-6-one and its 7-substituted analogues
Vaid, Radhe K.,Spitler, Jeremy T.,Boini, Sathish,May, Scott A.,Hoying, Richard C.
, p. 2396 - 2400 (2012)
An efficient synthesis of 4-chloro-2-pyrrolino[2,3-d]pyrimidin-6-one was achieved in four steps starting from dimethyl malonate in 23% overall yield. This synthesis was demonstrated on 100 g scale to obtain 4-chloro-2-pyrrolino[2, 3-d]pyrimidin-6-one in 9
AKT AND P70 S6 KINASE INHIBITORS
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Page/Page column 25, (2010/06/11)
The present invention provides AKT and p70 S6 kinase inhibitors of the formula: The present invention also provides pharmaceutical compositions comprising compounds of Formula I, uses of compounds of Formula I and methods of using compounds of Formula I.
