1226889-67-3Relevant academic research and scientific papers
Nickel- and copper-catalyzed direct alkynylation of azoles and polyfluoroarenes with terminal alkynes under O2 or atmospheric conditions
Matsuyama, Naoto,Kitahara, Masanori,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
scheme or table, p. 2358 - 2361 (2010/07/06)
The direct C-H alkynylation of azoles with terminal alkynes proceeds efficiently under a nickel/O2 catalytic system. On the other hand, a copper/air catalyst enables the coupling of polyfluoroarenes with terminal alkynes. These catalyses provide new accesses to arylacetylenes through the formal direct Sonogashira coupling.
