122690-86-2

Upstream product

• 103131-25-5 (2S,6R)-6-Hydroxymethyl-2-methyl-cyclohex-3-enecarboxylic acid methyl ester 
• 16298-49-0 (2S,6R)-6-Formyl-2-methyl-cyclohex-3-enecarboxylic acid methyl ester 
• 122690-76-0 (3aR,7S,7aS)-7-Methyl-3a,4,7,7a-tetrahydro-3H-isobenzofuran-1-one 
• 15941-50-1 (+/-)-3c-methyl-cyclohex-4-ene-1r,2c-dicarboxylic acid 
• 122690-78-2 (1R,2S,6R)-6-(2-Benzyloxymethyl-1-hydroxy-allyl)-2-methyl-cyclohex-3-enecarboxylic acid methyl ester 

Downstream Products

• 122690-82-8 (4S,6R,9aS)-8-Benzyloxymethyl-6-methoxy-4-methyl-5-trimethylsilanyloxy-1,6,7,9a-tetrahydro-4H-benzocycloheptene-6-carboxylic acid tert-butyl ester 
• 122690-82-8 (4R,6R,9aR)-8-Benzyloxymethyl-6-methoxy-4-methyl-5-trimethylsilanyloxy-1,6,7,9a-tetrahydro-4H-benzocycloheptene-6-carboxylic acid tert-butyl ester 
• 122690-84-0 (4R,4aS,6R,9aR)-8-Benzyloxymethyl-6-methoxy-4-methyl-5-oxo-1,4a,5,6,7,9a-hexahydro-4H-benzocycloheptene-6-carboxylic acid tert-butyl ester 
• 122690-84-0 (4R,4aR,6R,9aR)-8-Benzyloxymethyl-6-methoxy-4-methyl-5-oxo-1,4a,5,6,7,9a-hexahydro-4H-benzocycloheptene-6-carboxylic acid tert-butyl ester 
• 122690-80-6 3-[(1R,2S,6S,7R)-7-(1-Benzyloxymethyl-vinyl)-2-methyl-bicyclo[4.1.0]hept-3-en-1-yl]-2-methoxy-3-oxo-propionic acid tert-butyl ester 
• 122690-79-3 (1S,2R,6R,7S)-7-(1-Benzyloxymethyl-vinyl)-2-methyl-bicyclo[4.1.0]hept-3-ene-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

STUDIES ON TUMOR PROMOTERS: V. COMPLEMENTARY 1,4-STEREOCONTROL IN PHORBOID CYCLOHEPTENE SYNTHESIS VIA THE DIVINYLCYCLOPROPANE REARRANGEMENT

Methodology for the synthesis of B-C ring precursors and analogs of the phorbol esters is described which allows for complementary 1,4-stereocontrol in the formation of seven-membered rings through the selective formation and rearrangement of vinyl enol cyclopropanes.