1226992-79-5Relevant articles and documents
Protein Kinase Conjugates and Inhibitors
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Paragraph 0785; 0786; 0787, (2017/07/14)
The invention relates to protein conjugates that contain a protein kinase containing a cysteine residue in the ATP binding site and an inhibitor that is covalently and irreversibly bonded to said cysteine residue, such that the activity of the protein kin
PYRIMIDINE DERIVATIVES AS PROTEIN TYROSINE KINASE 2 INHIBITORS
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Page/Page column 36; 37, (2011/04/25)
The present invention encompasses compounds of general formulae (1a) and (1b), wherein the groups R1 to R5, A, Q, m, n, p and q are defined as in claim 1, which are FAK/PTK2 inhibitors and thus suitable for the treatment of diseases
NEW COMPOUNDS
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Page/Page column 24, (2010/07/10)
The present invention includes compounds of general Formula (1), wherein A, X, R1 and R2 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use for preparing a medicament having the above-mentioned properties.